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The Drug-Induced Respiratory Disease Website

See under Ix. A disease of the pleuropulmonary interface (see under Ix). PPFE has a predilection to involve the apical visceral pleural surface. More progressive and aggressive than the apical cap (Vt). Cases have been described in hematopoietic and lung transplant recipients (PMID 14627569, 23277524). PPFE may also occur as a complication of drugs or randomly and idiopathically (IPPFE). PPFE may overlap with upper lobe fibrosis

Publications

Marathe PH, Santibanez V, Meyers PA, Padilla ML, Friedman DN

Pleuroparenchymal fibroelastosis as a late complication of childhood cancer therapy: A case series.

Pediatric blood & cancer 2024 Jul;71;e31004 — 2024 Jul — e31004

Camus P, von der Thüsen J, Hansell DM, Colby TV

Pleuroparenchymal fibroelastosis: one more walk on the wild side of drugs?

The European respiratory journal 2014 Aug;44;289-96 — 2014 Aug — 289-96

Beynat-Mouterde C, Beltramo G, Lezmi G, Pernet D, Camus C, Fanton A, Foucher P, Cottin V, Bonniaud P

Pleuroparenchymal fibroelastosis as a late complication of chemotherapy agents.

The European respiratory journal 2014 Aug;44;523-7 — 2014 Aug — 523-7