The Drug-Induced Respiratory Disease Website
Can be uni- or bilateral. Pneumomediastinum can be present as an associated finding. Pneumothorax can develop as a complication of drug-induced pleural fibrosis or fibroelastosis (see under IV c) and it can difficult to treat as the lung may reexpand poorly. Pneumothorax can also occur as a complication of drug-induced cavitation or thinning of pulmonary tumors including metastases (See XIu). The association with therapy with drugs is confounded by indication (PMID 23801882) as pneumothorax can also occur idiopathically. Novel targeted agents may cause tumor necrosis, cavitation of metastatic lung nodules and difficult-to-treat pneumothorax
Publications
Reporting of pneumothorax in association with vaping devices and electronic cigarettes.
BMJ case reports 2021 Dec 17;14; — 2021 Dec 17
Bonilla A, Blair AJ, Alamro SM, Ward RA, Feldman MB, Dutko RA, Karagounis TK, Johnson AL, Folch EE, Vyas JM
Recurrent spontaneous pneumothoraces and vaping in an 18-year-old man: a case report and review of the literature.
Journal of medical case reports 2019 Sep 09;13;283 — 2019 Sep 09 — 283