The Drug-Induced Respiratory Disease Website

Nasal, palatal and/or pharyngeal pathology

See also under central destructive lesions. And under PMID 33813873.

Hussaini AS, Black CK, Malekzadeh S, Milmoe GJ

Extensive Sinonasal and Oropharyngeal Necrosis as a Consequence of Adulterated Cocaine with Mimicry of ANCA-Positive Vasculitis.

OTO open 2019 Oct-Dec;3;2473974X19894239 — 2019 Oct-Dec — 2473974X19894239

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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