The Drug-Induced Respiratory Disease Website

Foreign body/substance pulmonary embolism

See also under VIg, VIe, VIh, XVag, XVai, XVbn

Boylan PM, Santibañez M, Lounsbury N, Eltaki SM

A nonthrombotic pulmonary embolus caused by polyalkylimide dermal filler: A case report and literature review of medication management.

Journal of the American Pharmacists Association : JAPhA 2021 Mar 11;; — 2021 Mar 11

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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