The Drug-Induced Respiratory Disease Website

Bosutinib

Pulmonary infiltrates

Sometimes not specified otherwise

Liu QS, Ass'ad NA, Arana Yi C

Bosutinib-associated interstitial lung disease and pleural effusion: A case report and literature review.

Clinical case reports 2021 May;9;e03164 — 2021 May — e03164

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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