Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XXIV.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812

Publications

Li S, Fang M, Guo H, Yu T, Wang J, Li W, Huang Y, Wang X, Wu R

Eosinophilic pulmonary disease with ulcerative colitis: A case report.

Medicine 2024 Apr 26;103;e37851 — 2024 Apr 26 — e37851

Pereira FM, Marques C, Boncoraglio T, Esteves J, Silva M, Braga J, Ribeiro M

Mesalazine-induced Hypersensitivity Pneumonitis.

European journal of case reports in internal medicine 2021;8;002194 — 2021 — 002194

Park M, Lee J, Kang SB, Park Y

Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2019 Apr 25;73;225-229 — 2019 Apr 25 — 225-229

Yeo J, Woo HS, Lee SM, Kim YJ, Kwon KA, Park DK, Kim JH, Kim KO, Chung JW

Drug-induced eosinophilic pneumonia in a patient with Crohn's disease: diagnosis and treatment using fraction of exhaled nitric oxide.

Intestinal research 2017 Oct;15;529-534 — 2017 Oct — 529-534

Gupta A, Gulati S

Mesalamine induced eosinophilic pneumonia.

Respiratory medicine case reports 2017;21;116-117 — 2017 — 116-117

Ferrusquía J, Pérez-Martínez I, Gómez de la Torre R, Fernández-Almira ML, de Francisco R, Rodrigo L, Riestra S

Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity.

World journal of gastroenterology 2015 Apr 07;21;4069-77 — 2015 Apr 07 — 4069-77

Michy B, Raymond S, Graffin B

[Organizing pneumonia during treatment with mesalazine].

Revue des maladies respiratoires 2014 Jan;31;70-7 — 2014 Jan — 70-7

Caccaro R, Savarino E, D'Incà R, Sturniolo GC

Noninfectious interstitial lung disease during infliximab therapy: case report and literature review.

World journal of gastroenterology 2013 Aug 28;19;5377-80 — 2013 Aug 28 — 5377-80

Kim JH, Lee JH, Koh ES, Park SW, Jang AS, Kim D, Park CS

Acute eosinophilic pneumonia related to a mesalazine suppository.

Asia Pacific allergy 2013 Apr;3;136-9 — 2013 Apr — 136-9

Saltzman K, Rossoff LJ, Gouda H, Tongia S

Mesalamine-induced unilateral eosinophilic pneumonia.

AJR. American journal of roentgenology 2001 Jul;177;257 — 2001 Jul — 257

Zamir D, Weizman J, Zamir C, Fireman Z, Weiner P

[Mesalamine-induced hypersensitivity pneumonitis].

Harefuah 1999 Jul;137;28-30, 87, 86 — 1999 Jul — 28-30, 87, 86

Lázaro MT, García-Tejero MT, Díaz-Lobato S

Mesalamine-induced lung disease.

Archives of internal medicine 1997 Feb 24;157;462 — 1997 Feb 24 — 462

Bitton A, Peppercorn MA, Hanrahan JP, Upton MP

Mesalamine-induced lung toxicity.

The American journal of gastroenterology 1996 May;91;1039-40 — 1996 May — 1039-40

Takahashi N, Aizawa H, Takata S, Matsumoto K, Koto H, Inoue H, Hara N

Acute interstitial pneumonitis induced by carbamazepine.

The European respiratory journal 1993 Oct;6;1409-11 — 1993 Oct — 1409-11

Honeybourne D

Mesalazine toxicity.

BMJ (Clinical research ed.) 1994 Feb 19;308;533-4 — 1994 Feb 19 — 533-4