The Drug-Induced Respiratory Disease Website
Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
Evidence level
low
Lone, isolated, free-flowing pleural effusion on imaging. See other forms of pleural effusions under Vb, d, e, g, h, i, m which may present similarly on imaging. The effusion can be uni- or bilateral. More often a lymphocyte-, mixed or neutrophil-rich exudate. At times the effusion is eosipophil-rich. Pleural effusion can be present with the acute clinical phase of severe drug-induced ILD (e.g. methotrexate lung; PMID 16840219). In general, pleural effusion in the context of drug-induced ILD or pulmonary edema is not tabulated under this heading. ANA-panel indicated to diagnose drug-induced lupus PMID 10424528
Publications
Mesalamine-associated pleural effusion with pulmonary infiltration.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1998 Nov 01;55;2304-5 — 1998 Nov 01 — 2304-5
Mesalazine toxicity.
BMJ (Clinical research ed.) 1994 Feb 19;308;533-4 — 1994 Feb 19 — 533-4