The Drug-Induced Respiratory Disease Website

Coronary artery disease (acute) - Myocardial ischemia/infarction

Including acute coronary artery disease or spasm and acute ST segment elevation on ECG/EKG. See also under Xg, XIIo and XIIaf

Kounis GN, Kouni SA, Hahalis G, Kounis NG

Mesalamine hypersensitivity and Kounis syndrome in a pediatric ulcerative colitis patient.

World journal of gastroenterology 2008 Dec 14;14;7141-2 — 2008 Dec 14 — 7141-2

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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