The Drug-Induced Respiratory Disease Website

An area or areas of consolidation

(Fr: foyers de condensation). See also under BOOP/organizing pneumonia, eosinophilic pneumonia, and in the Imaging section (XVI).

Huang PH, Kuo CJ, Lin CW, Cheng YM, Hu HC, Lin CY, Su MY, Chiu CT

Mesalazine-related lung disease in a patient with ulcerative colitis: A case report.

Medicine 2018 Nov;97;e13242 — 2018 Nov — e13242

Wang IJ, Lin CC, Lin YJ, Hsieh WS, Chen PC

Early life phthalate exposure and atopic disorders in children: a prospective birth cohort study.

Environment international 2014 Jan;62;48-54 — 2014 Jan — 48-54

Kim JH, Lee JH, Koh ES, Park SW, Jang AS, Kim D, Park CS

Acute eosinophilic pneumonia related to a mesalazine suppository.

Asia Pacific allergy 2013 Apr;3;136-9 — 2013 Apr — 136-9

Kevans D, Greene J, Galvin L, Morgan R, Murray FE

Mesalazine-induced bronchiolitis obliterans organizing pneumonia (BOOP) in a patient with ulcerative colitis and primary sclerosing cholangitis.

Inflammatory bowel diseases 2011 Oct;17;E137-8 — 2011 Oct — E137-8

Camus P, Piard F, Ashcroft T, Gal AA, Colby TV

The lung in inflammatory bowel disease.

Medicine 1993 May;72;151-83 — 1993 May — 151-83

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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