The Drug-Induced Respiratory Disease Website

Durvalumab

Path: Myocarditis

Maetani T, Hamaguchi T, Nishimura T, Marumo S, Fukui M

Durvalumab-associated Late-onset Myocarditis Successfully Treated with Corticosteroid Therapy.

Internal medicine (Tokyo, Japan) 2021 Aug 24;; — 2021 Aug 24

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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