The Drug-Induced Respiratory Disease Website

Coronavirus (SARS-COVID19) vaccination/vaccine

Guillain-Barré (or GB-like) syndrome (w/wo ARF)

ARF: acute resiratory failure

Publications

Lahoz Fernandez PE, Miranda Pereira J, Fonseca Risso I, Baleeiro Rodrigues Silva P, Freitas Barboza IC, Vieira Silveira CG, Diogo Silva G, Marzorati Kuntz Puglia P, Genaro Mutarelli E

Guillain-Barre syndrome following COVID-19 vaccines: A scoping review.

Acta neurologica Scandinavica 2021 Dec 29;; — 2021 Dec 29

Introna A, Caputo F, Santoro C, Guerra T, Ucci M, Mezzapesa DM, Trojano M

Guillain-Barré syndrome after AstraZeneca COVID-19-vaccination: A causal or casual association?

Clinical neurology and neurosurgery 2021 Aug 13;208;106887 — 2021 Aug 13 — 106887

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

Diagnosing DIRD

Identify causative drugs

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