The Drug-Induced Respiratory Disease Website

Coronavirus (SARS-COVID19) vaccination/vaccine

Exacerbation or deterioration of preexisting asthma

Uzer F, Cilli A

Acute asthma exacerbation after SARS-CoV-2 vaccine (Sinovac®): a case report.

Medical gas research 2022 Apr-Jun;12;67-68 — 2022 Apr-Jun — 67-68

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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