The Drug-Induced Respiratory Disease Website

Cryobiopsy (transbronchial pulmonary - TBLB-TBLCB)

Pulmonary hematoma

(Fr: hématome pulmonaire)

Hackner K, Stadler A, Schragel F, Klamminger V, Ghanim B, Varga A, Errhalt P

Transbronchial lung cryobiopsy: prospective safety evaluation and 90-day mortality after a standardized examination protocol.

Therapeutic advances in respiratory disease 2022 Jan-Dec;16;17534666221077562 — 2022 Jan-Dec — 17534666221077562

Ueno H, Tsubouchi H, Nakanishi K, Sugiyama T, Kadomatsu Y, Goto M, Ozeki N, Nakamura S, Fukui T, Chen-Yoshikawa TF

Removal of hematoma due to massive hemoptysis after transbronchial biopsy: a case report.

Surgical case reports 2021 Nov 03;7;237 — 2021 Nov 03 — 237

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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