The Drug-Induced Respiratory Disease Website

Coronavirus (SARS-COVID19) vaccination/vaccine

Imaging: Asymmetrical, predominantly unilateral involvement

Corresponding to unilateral ILD or pulmonary edema

Miqdadi A, Herrag M

Acute Eosinophilic Pneumonia Associated With the Anti-COVID-19 Vaccine AZD1222.

Cureus 2021 Oct;13;e18959 — 2021 Oct — e18959

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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