The Drug-Induced Respiratory Disease Website

Amiodarone

Pulmonary infiltrates

Sometimes not specified otherwise

Rôlo Silvestre CM, Nunes A, Cordeiro RJ, Eusébio JP, Vilaça MT, Falcão T, Domingos AC

From the Heart to the Lung: A Case of Drug Toxicity.

The American journal of case reports 2021 Apr 06;22;e929906 — 2021 Apr 06 — e929906

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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