The Drug-Induced Respiratory Disease Website

Lithium, lithium poisoning

Heart block (bundle branch- or AV-)

AV block may be complete and/or irreversible

Kalpakos T, Vermeersch G, Hendriks B, Vermeersch P

Complete atrioventricular block with diastolic mitral regurgitation due to severe lithium intoxication. A case report.

Acta cardiologica 2022 Mar 24;;1-6 — 2022 Mar 24 — 1-6

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.