The Drug-Induced Respiratory Disease Website
See also PMIDs 31612562, 34359324. Several drugs can cause a mimic of naturally-occurring endo- and/or extra-thoracic sarcoid-like reaction/sarcoidosis, or a flare of previously diagnosed sarcoidosis (particularly with the use of interferon, anti-TNF agents, or immune checkpoint inhibitors (PMID: 27504482). Both the timing of exposure to the drug and the effect of discontinuation are important to evaluate whether the condition is drug-related. Examination of the skin including scars and/or tatoo edges for evidence of granuloma can be rewarding (PMIDs 24239377, 33905479, 34359324). See also under VIIa, VIIe, Xl.
Publications
Tronconi MC, Marinello A, Solferino A, Grimaudo S, Ciccarelli M, Manara S, Cozzaglio L, Mancini L, Borroni R, Santoro A
A Case of Pulmonary Sarcoidosis during First-Line Targeted Therapy with Dabrafenib Plus Trametinib in V600E-Mutated Metastatic Melanoma.
Case reports in oncology 2022 May-Aug;15;560-565 — 2022 May-Aug — 560-565