The Drug-Induced Respiratory Disease Website

Constrictive pericarditis - Pericardial thickening

Hanif MA, Shrestha B, Hanif H, Shahzad A, Suwal A, Shah S, Oladiran O, Macciocca M, Donato AA

Constrictive Pericarditis from an Atraumatic Hemopericardium After Systemic Thrombolysis for a Massive Pulmonary Embolism.

Journal of community hospital internal medicine perspectives 2023;13;46-48 — 2023 — 46-48

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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