The Drug-Induced Respiratory Disease Website

Pembrolizumab

Polymyalgia rheumatica

May cause blindness (PMID 30442497)

Ramirez-Poza S, Pardo-Cabello AJ, Salvatierra J

Polymyalgia rheumatica after pembrolizumab treatment.

Medicina clinica 2023 Sep 29;161;270-271 — 2023 Sep 29 — 270-271

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.