Philippe Camus, M.D.

Dijon, France

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XXII.b

Acute lung injury - ARDS

(Fr: SDRA sur critères gazométriques PaO2/FIO2). May overlap with Ia. Mechanical ventilation commonly needed. ECMO required in some instances (PMID 29967877). ARDS definition and grading at PMID 22797452. ARDS (and formerly ALI) are defined on the basis of gas exchange abnormalities. Thus, ARDS is not a well-characterized disease entity and may arise in widely disparate clinical scenarios. Pathologically, ARDS may correspond to DAD, pulmonary edema, acute NSIP-like ILD w/wo granulomas, -eosinophilic pneumonia (AEP), AFOP, amiodarone pulmonary toxicity, DAH, fat or silicone embolism, AIP, radiation injury, pulmonary fibrosis exacerbated by drugs or surgery (see under specific patterns) and drug- or alcohol-induced aspiration pneumonitis (see under XIg). Appropriate tests and BAL help exclude an infection and separate these entities. Some patients respond to intravenous corticosteroid therapy. Review at PMID 1939859. See also under IL 'Diffuse Alveolar Damage', XIg, XVf and under 'Postoperative ARDS'

Publications

Gibelin A, Parrot A, Maitre B, Brun-Buisson C, Mekontso Dessap A, Fartoukh M, de Prost N

Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.

Intensive care medicine 2016 Feb;42;164-72 — 2016 Feb — 164-72

Tu GW, Ju MJ, Xu M, Rong RM, Zhu TY, Luo Z

Antithymocyte globulin-induced acute respiratory distress syndrome after renal transplantation: a case report.

Chinese medical journal 2012 May;125;1664-6 — 2012 May — 1664-6

Oberoi S, Bansal D, Sharma RR, Gautam V, Marwaha N, Marwaha RK

Antithymocyte globulin-induced acute lung injury during transplantation for aplastic anemia.

Journal of pediatric hematology/oncology 2011 Mar;33;150-2 — 2011 Mar — 150-2

Shorr AF, Abbott KC, Agadoa LY

Acute respiratory distress syndrome after kidney transplantation: epidemiology, risk factors, and outcomes.

Critical care medicine 2003 May;31;1325-30 — 2003 May — 1325-30

Maillard N, Foucher P, Caillot D, Durand C, Sgro C, Camus P

Transient pulmonary infiltrates during treatment with anti-thymocyte globulin.

Respiration; international review of thoracic diseases 1999;66;279-82 — 1999 — 279-82

Dean NC, Amend WC, Matthay MA

Adult respiratory distress syndrome related to antilymphocyte globulin therapy.

Chest 1987 Apr;91;619-20 — 1987 Apr — 619-20

Murdock DK, Lawless CE, Collins E, Huml JP, Pifarre R

ARDS following equine ATG therapy.

Chest 1987 Sep;92;578 — 1987 Sep — 578