The Drug-Induced Respiratory Disease Website

Venetoclax

Rechallenge can lead to relapse of AE/ILD

When available, likelihood and risk given for specific drug

Siddiqui AS

Venetoclax-associated interstitial pneumonitis.

Respiratory medicine case reports 2024;50;102038 — 2024 — 102038

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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