The Drug-Induced Respiratory Disease Website

Mercury (fluid) p.o.

Imaging: Metallic densities in trachea or large airways

Tsuji HK, Tyler GC, Redington JV, Kay JH

Intrabronchial metallic mercury.

Chest 1970 Apr;57;322-8 — 1970 Apr — 322-8

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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