The Drug-Induced Respiratory Disease Website

Beta-blockers

Bronchospasm - Wheezing - Asthma

Can be life-threatening. Risk varies with beta-1 selectivity (PMID 24202435). Persistent asthma occasionally follows beta-blocker-induced bronchospasm (PMID 45308)

Publications

Wu JH, Jerng JS, Su CC

Insidious-onset, non-wheezing carteolol-induced asthma in an atopic patient without asthma history.

BMJ case reports 2019 Apr 04;12; — 2019 Apr 04

Morales DR, Jackson C, Lipworth BJ, Donnan PT, Guthrie B

Adverse respiratory effect of acute ?-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials.

Chest 2014 Apr;145;779-786 — 2014 Apr — 779-786

Shepherd D, Adams S, Wargon O, Jaffe A

Childhood wheeze while taking propranolol for treatment of infantile hemangiomas.

Pediatric pulmonology 2012 Jul;47;713-5 — 2012 Jul — 713-5

Miki A, Tanaka Y, Ohtani H, Sawada Y

Betaxolol-induced deterioration of asthma and a pharmacodynamic analysis based on beta-receptor occupancy.

International journal of clinical pharmacology and therapeutics 2003 Aug;41;358-64 — 2003 Aug — 358-64

Hoigné RV, Braunschweig S, Zehnder D, Kuenzi UP, Hess T, Leuenberger P

Drug-induced attack of bronchial asthma in inpatients: a 20-year survey of the Comprehensive Hospital Drug Monitoring Programme on adverse drug reactions, Berne/St. Gallen.

European journal of clinical pharmacology 1997;53;81-2 — 1997 — 81-2

Patakas D, Argiropoulou V, Louridas G, Tsara V

Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways.

Thorax 1983 Feb;38;108-12 — 1983 Feb — 108-12

Lawrence DS, Sahay JN, Chatterjee SS, Cruickshank JM

Asthma and beta-blockers.

European journal of clinical pharmacology 1982;22;501-9 — 1982 — 501-9

Anderson EG, Calcraft B, Jariwalla AG, Al-Zaibak M

Persistent asthma after treatment with beta-blocking agents.

British journal of diseases of the chest 1979 Oct;73;407-8 — 1979 Oct — 407-8

Decalmer PB, Chatterjee SS, Cruickshank JM, Benson MK, Sterling GM

Beta-blockers and asthma.