The Drug-Induced Respiratory Disease Website
(Fr: SDRA sur critères gazométriques PaO2/FIO2). May overlap with Ia. Mechanical ventilation commonly needed. ECMO required in some instances (PMID 29967877). ARDS definition and grading at PMID 22797452. ARDS (and formerly ALI) are defined on the basis of gas exchange abnormalities. Thus, ARDS is not a well-characterized disease entity and may arise in widely disparate clinical scenarios. Pathologically, ARDS may correspond to DAD, pulmonary edema, acute NSIP-like ILD w/wo granulomas, -eosinophilic pneumonia (AEP), AFOP, amiodarone pulmonary toxicity, DAH, fat or silicone embolism, AIP, radiation injury, pulmonary fibrosis exacerbated by drugs or surgery (see under specific patterns) and drug- or alcohol-induced aspiration pneumonitis (see under XIg). Appropriate tests and BAL help exclude an infection and separate these entities. Some patients respond to intravenous corticosteroid therapy. Review at PMID 1939859. See also under IL 'Diffuse Alveolar Damage', XIg, XVf and under 'Postoperative ARDS'
Publications
Hemoadsorption to treat severe iatrogenic intoxication with Patent Blue: a case report.
Journal of medical case reports 2021 Feb 09;15;63 — 2021 Feb 09 — 63
Isolated non-cardiogenic pulmonary edema - A rare complication of MDMA toxicity.
The American journal of emergency medicine 2017 Sep;35;1385.e3-1385.e6 — 2017 Sep — 1385.e3-1385.e6
Ecstasy--deadly risk even outside rave parties.
Forensic science international 2005 Oct 29;153;227-30 — 2005 Oct 29 — 227-30
Fatal multi-organ failure after suicidal overdose with MDMA, 'ecstasy': case report and review of the literature.
Human & experimental toxicology 1999 Feb;18;119-25 — 1999 Feb — 119-25
An unusual case of Ecstasy poisoning.
Intensive care medicine 1996 Jul;22;670-1 — 1996 Jul — 670-1
'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA.
JAMA 1987 Mar 27;257;1615-7 — 1987 Mar 27 — 1615-7