The Drug-Induced Respiratory Disease Website

Household/cleansing/cleaning agents

Incl. aerosolized cleansing agents and disinfectants. Please refer to compounds listed on right under 'See also'

Respiratory distress or failure, not otherwise specified

Pneumonitis (ILD), acute and/or severe (may cause ARDS)

Thermal (burns, frostbite), chemical or caustic injury (face, buccal mucosa, pharynx, upper airway)

Obliterative bronchiolitis (an imaging and/or pathological pattern consistent with)

Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)

Esophageal stenosis/stricture

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

No activity has been recorded yet.