Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

II.a

Left ventricular dysfunction/failure

De novo chronic, progressive or acute LV dysfunction/failure. May result from myocarditis or eosinophilic myocarditis. May cause congestive heart failure and/or pulmonary edema (see under II). Hypertension may be present. Symptoms range from worsening of preexisting LVF to acute cardiogenic pulmonary edema, shock or cardiopulmonary arrest. See also pulmonary edema under IId, and XIId, XIIf. Review at PMID 10193711, 16808550, 18083403, 21930637

Publications

Gündo?an C, Erol Ö, Beyhan E, Gürsu RU, Çermik TF

Findings of congestive heart failure associated with sunitinib cardiotoxicity in F-FDG PET/CT.

Revista espanola de medicina nuclear e imagen molecular 2022 May-Jun;41;197-198 — 2022 May-Jun — 197-198

Skubitz KM

Cardiotoxicity Monitoring in Patients Treated with Tyrosine Kinase Inhibitors.

The oncologist 2019 Apr 10;; — 2019 Apr 10

Boyle HJ, Chatté G, Rivoire M, Fléchon A

Lung toxicity in a patient treated with sunitinib.

The European respiratory journal 2012 Nov;40;1300-3 — 2012 Nov — 1300-3

Kirk R

Targeted therapies: Risk of heart failure with sunitinib.

Nature reviews. Clinical oncology 2011 Aug 16;8;569 — 2011 Aug 16 — 569

Richards CJ, Je Y, Schutz FA, Heng DY, Dallabrida SM, Moslehi JJ, Choueiri TK

Incidence and risk of congestive heart failure in patients with renal and nonrenal cell carcinoma treated with sunitinib.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Sep 01;29;3450-6 — 2011 Sep 01 — 3450-6

Schmidinger M, Bojic A, Vogl UM, Lamm W, Zielinski CC

Management of cardiac adverse events occurring with sunitinib treatment.

Anticancer research 2009 May;29;1627-9 — 2009 May — 1627-9

Telli ML, Witteles RM, Fisher GA, Srinivas S

Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate.

Annals of oncology : official journal of the European Society for Medical Oncology 2008 Sep;19;1613-8 — 2008 Sep — 1613-8

Khakoo AY, Kassiotis CM, Tannir N, Plana JC, Halushka M, Bickford C, Trent J, Champion JC, Durand JB, Lenihan DJ

Heart failure associated with sunitinib malate: a multitargeted receptor tyrosine kinase inhibitor.

Cancer 2008 Jun;112;2500-8 — 2008 Jun — 2500-8

Machiels JP, Bletard N, Pirenne P, Jacquet L, Bonbled F, Duck L

Acute cardiac failure after sunitinib.

Annals of oncology : official journal of the European Society for Medical Oncology 2008 Mar;19;597-9 — 2008 Mar — 597-9

Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, Schoen FJ, Van den Abbeele AD, Demetri GD, Force T, Chen MH

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib.

Lancet (London, England) 2007 Dec 15;370;2011-9 — 2007 Dec 15 — 2011-9