The Drug-Induced Respiratory Disease Website

Adenosine

Cardiac- cardiorespiratory/pulmonary arrest

Plaschke K, Böckler D, Schumacher H, Martin E, Bardenheuer HJ

Adenosine-induced cardiac arrest and EEG changes in patients with thoracic aorta endovascular repair.

British journal of anaesthesia 2006 Mar;96;310-6 — 2006 Mar — 310-6

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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