Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XXII.e

Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

Presentation may range from restrictive lung dysfunction to acute respiratory failure with an increased PaCO2 and respiratory acidosis and blunted ventilatory reponse to hypoxia and/or hypercarbia. Aspiration, brain damage and death can occur (See PMID 25536092). See also under IXi, IXIe, IXa, IXj, IXs.

Publications

Bugay V, Gregory SR, Belanger-Coast MG, Zhao R, Brenner R

Effects of Sublethal Organophosphate Toxicity and Anti-cholinergics on Electroencephalogram and Respiratory Mechanics in Mice.

Frontiers in neuroscience 2022;16;866899 — 2022 — 866899

Shaikh S, Khaskheli MS, Meraj M, Raza H

Effect of Organophasphate poisoning among patients reporting at a tertiary healthcare facility of Sindh Pakistan.

Pakistan journal of medical sciences 2018 May-Jun;34;719-723 — 2018 May-Jun — 719-723

Vale A

Organophosphorus insecticide poisoning.

BMJ clinical evidence 2015 Nov 30;2015; — 2015 Nov 30

Hulse EJ, Davies JO, Simpson AJ, Sciuto AM, Eddleston M

Respiratory complications of organophosphorus nerve agent and insecticide poisoning. Implications for respiratory and critical care.

American journal of respiratory and critical care medicine 2014 Dec 15;190;1342-54 — 2014 Dec 15 — 1342-54

Carey JL, Dunn C, Gaspari RJ

Central respiratory failure during acute organophosphate poisoning.

Respiratory physiology & neurobiology 2013 Nov 01;189;403-10 — 2013 Nov 01 — 403-10