Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XXII.e

Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

Presentation may range from restrictive lung dysfunction to acute respiratory failure with an increased PaCO2 and respiratory acidosis and blunted ventilatory reponse to hypoxia and/or hypercarbia. Aspiration, brain damage and death can occur (See PMID 25536092). See also under IXi, IXIe, IXa, IXj, IXs.

Publications

Lyndon A, Audrey S, Wells C, Burnell ES, Ingle S, Hill R, Hickman M, Henderson G

Risk to heroin users of polydrug use of pregabalin or gabapentin.

Addiction (Abingdon, England) 2017 Sep;112;1580-1589 — 2017 Sep — 1580-1589

Wood DM, Berry DJ, Glover G, Eastwood J, Dargan PI

Significant pregabalin toxicity managed with supportive care alone.

Journal of medical toxicology : official journal of the American College of Medical Toxicology 2010 Dec;6;435-7 — 2010 Dec — 435-7