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The Drug-Induced Respiratory Disease Website

Usually , subacute/chronic, lone, with no definite evidence for underlying involvement, disease or explanation. A workup for drug-induced asthma, the 'locked lung', pulmonary embolism, and hemoglobinpathies is required. Ticagrelor is a significant etiologic contributor to this pattern

Publications

Unverdorben M, Parodi G, Pistolesi M, Storey RF

Dyspnea related to reversibly-binding P2Y12 inhibitors: A review of the pathophysiology, clinical presentation and diagnostics.

International journal of cardiology 2016 Jan 01;202;167-73 — 2016 Jan 01 — 167-73

Serebruany VL, Sibbing D, DiNicolantonio JJ

Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond.

Cardiology 2014;127;20-4 — 2014 — 20-4

Serebruany VL

Viewpoint: reversible nature of platelet binding causing transfusion-related acute lung injury (TRALI) syndrome may explain dyspnea after ticagrelor and elinogrel.

Thrombosis and haemostasis 2012 Dec;108;1024-7 — 2012 Dec — 1024-7