The Drug-Induced Respiratory Disease Website

Amitraz

Acute respiratory or cardiopulmonary failure

With or without demonstrable pulmonary opacities. Mechanical ventilation is often required. See also under Ia, IIa, IIb, IXa, IXd, IXj

Dhooria S, Agarwal R

Amitraz, an underrecognized poison: A systematic review.

The Indian journal of medical research 2016 Sep;144;348-358 — 2016 Sep — 348-358

Agrawal I, Ahmad S, Kumar M, Akram M

Amitraz poisoning: an unusual cause of respiratory and peripheral circulatory failure.

Tropical doctor 2017 Jul;47;266-268 — 2017 Jul — 266-268

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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