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The Drug-Induced Respiratory Disease Website

Of note, peritracheal and/or submucosal air/gas may obstruct the upper/central airway causing asphyxia. See also under Vf. Pneumomediastinum may cause mediastinal shift or compression with consequent UAO and/or acute respiratory failure (PMID 19748792; 31737371). Pneumomediastinum can also be observed as a complication of drug-induced ILD, pulmonary fibrosis or ARDS, either spontaneously or as a consequence of barotrauma (e.g. with pulmonary function testing or mechanical ventilation).

Publications

Iqbal M, Hussain A, Majeed Z, Elfaki H

Pneumomediastinum in a cannabis smoker precipitated by vigorous sexual intercourse.

BMJ case reports 2021 Sep 03;14; — 2021 Sep 03

Puri C, Rhee K, Harish VK, Slack D

Marijuana induced spontaneous pneumomediastinum.

Journal of community hospital internal medicine perspectives 2021 Jun 21;11;516-517 — 2021 Jun 21 — 516-517

Weiss ZF, Gore S, Foderaro A

Pneumomediastinum in marijuana users: a retrospective review of 14 cases.

BMJ open respiratory research 2019;6;e000391 — 2019 — e000391

Iyer VN, Joshi AY, Ryu JH

Spontaneous pneumomediastinum: analysis of 62 consecutive adult patients.

Mayo Clinic proceedings 2009 May;84;417-21 — 2009 May — 417-21