The Drug-Induced Respiratory Disease Website

Benzbromarone

Pleuritic chest pain

Can be transfixiating. Exaggerated at end-inspiration. See also under pleural involvement (Vi, Vo) and XIb

Hara A, Mukae H, Hara S, Amenomori M, Ishimoto H, Kakugawa T, Fujita H, Sakamoto N, Ishii H, Ishimatsu Y, Kohno S

Drug-induced eosinophilic pneumonia with pulmonary alveolar hemorrhage caused by benzbromarone.

Internal medicine (Tokyo, Japan) 2010;49;435-8 — 2010 — 435-8

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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