The Drug-Induced Respiratory Disease Website

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.n Respiratory arrest - Apnea

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.d Eosinophilic pleural effusion

XV. Chest pain

XV.a Chest pain (acute or subacute), lone or prominent

XV. Chest pain

XV.b Pleuritic chest pain

XV. Chest pain

XV.e Pleuritis (can cause chest pain)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XXI. Mediastinal involvement/injury

XXI.a Lymphadenopathy (intrathoracic)

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.d Acute eosinophilic pneumonia (AEP)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.f Diffuse alveolar damage (DAD) imaging pattern

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.ab Chronic pneumonitis/ILD

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.ah Transient pulmonary opacities/infiltrates (see also under Iav)

XXV. Pulmonary function - Pulmonary physiology - PFTs

XXV.i A restrictive lung function defect

XXVIII. Large airway involvement

XXVIII.o A ‘tracheobronchitis’ clinical pattern

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXX. Imaging features

XXX.u Imaging: Reverse ventilation-perfusion mismatch

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.u Pulmonary vasculitis or capillaritis