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Include destruction of the turbinates, nasal septum and ulceration and perforation of the hard palate. May mimic the clinical ENT manifestations and some of the laboratory features of granulomatous polyangiitis (formerly known as Wegener). Up to half the patients may demonstrate positive ANCA staining. Osteomyelitis and fungal colonization or infection may develop (PMID: 11605572, 25229300). See also under Xm, Xs( ANCA-positive vasculitis) and Xx

Publications

Ruffer N, Krusche M, Holl-Ulrich K, Kötter I, Lötscher F

[Cocaine-induced vasculitis and mimics of vasculitis].

Zeitschrift fur Rheumatologie 2023 Sep;82;606-614 — 2023 Sep — 606-614

Hussaini AS, Black CK, Malekzadeh S, Milmoe GJ

Extensive Sinonasal and Oropharyngeal Necrosis as a Consequence of Adulterated Cocaine with Mimicry of ANCA-Positive Vasculitis.

OTO open 2019 Oct-Dec;3;2473974X19894239 — 2019 Oct-Dec — 2473974X19894239