XXXI - Eye catchers
Midline destructive lesions
Last update 17/06/2026
Include destruction of the turbinates, nasal septum and ulceration and perforation of the hard palate. May mimic the clinical ENT manifestations and some of the laboratory features of granulomatous polyangiitis (formerly known as Wegener). Up to half the patients may demonstrate positive ANCA staining. Osteomyelitis and fungal colonization or infection may develop (PMID: 11605572, 25229300). See also under Xm, Xs( ANCA-positive vasculitis) and Xx