The Drug-Induced Respiratory Disease Website

Kratom (Mitragynine)

Acute respiratory or cardiopulmonary failure

With or without demonstrable pulmonary opacities. Mechanical ventilation is often required. See also under Ia, IIa, IIb, IXa, IXd, IXj

Hall A, Hall D

Kratom Ingestion and Emergency Care: Summary and a Case Report.

Journal of emergency nursing 2021 Apr 13;; — 2021 Apr 13

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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