The Drug-Induced Respiratory Disease Website

Infliximab

Right ventricular thrombus/thrombosis

Ogilvie JA, Iraqi A, Haas C, Bharaj R

Right ventricular thrombus and pulmonary embolism after infliximab therapy for ulcerative colitis.

BMJ case reports 2021 Jun 28;14; — 2021 Jun 28

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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