The Drug-Induced Respiratory Disease Website

Vicks Vaporub TM (R)

Multiple organ dysfunction/failure (MODS/MOF)

Cordoba Torres IT, Marino-Nieto J, Barkin HB, Fort AC, Cobas M

Vicks® VapoRub™ intoxication: An unusual presentation of multiorgan failure.

Journal of clinical anesthesia 2018 08;48;46-47 — 2018 08 — 46-47

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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