The Drug-Induced Respiratory Disease Website

Catheter ablation for atrial fibrillation

Hematoma of/around central airway wall potentially causing UAO

UAO: upper airway obstruction. Hematoma may localize in the mouth floor, tongue, retropharyngeal space, epiglottis, airway wall or localize in the mediastinum around the airway potentially causing UAO

Publications

Waleed KB, Toor P, Akhtar Z, Aron J, Govewalla P, Gallagher MM

Stridor and dyspnoea after ablation for atrial fibrillation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2023 Feb 08;25;129 — 2023 Feb 08 — 129

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

Diagnosing DIRD

Identify causative drugs

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