The Drug-Induced Respiratory Disease Website

XII. Pericardial involvement

XII.c Hemopericardium - Bloody pericardial effusion

XIV. Pleural involvement

XIV.e Hemothorax - Serosanguineous pleural effusion

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.h Coagulopathy

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.l Thoracic epidural or spinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.o Epistaxis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XII. Pericardial involvement

XII.c Hemopericardium - Bloody pericardial effusion

XIV. Pleural involvement

XIV.e Hemothorax - Serosanguineous pleural effusion

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.a Hemomediastinum - Mediastinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.b Pulmonary hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.d Retropharyngeal hematoma (may cause UAO)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.k Vocal cord hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.l Thoracic epidural or spinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.m BAL: Gross or microscopic bleeding/hemorrhage

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.n Rectus abdominis sheath hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.o Epistaxis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.i Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXVIII. Large airway involvement

XXVIII.i Tongue involvement (edema, glossitis, hematoma)

XXXII. Esophageal pathology

XXXII.a Esophageal hematoma (may cause chest pain and/or tracheal compression)

XXXVII. Veterinary medicine and pathology

XXXVII.e Veterinary: (Peri-) tracheal/retropharyngeal hemorrhage

XXXVIII. Miscellaneous - Varia

XXXVIII.l Calcification of tracheobronchial cartilaginous rings

XI. Pulmonary vasculopathies

XI.g Pulmonary vein stenosis

XII. Pericardial involvement

XII.k Pneumopericardium

XII. Pericardial involvement

XII.m Pericardial-esophageal fistula

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.j Major/massive hemoptysis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

V. Myocarditis

V.a Myocarditis (can be fulminate/fulminant)

VIII. Valvular heart disease

VIII.a Valvular heart disease and/or dysfunction

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.n Respiratory arrest - Apnea

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.d Eosinophilic pleural effusion

XV. Chest pain

XV.a Chest pain (acute or subacute), lone or prominent

XV. Chest pain

XV.b Pleuritic chest pain

XV. Chest pain

XV.e Pleuritis (can cause chest pain)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XXI. Mediastinal involvement/injury

XXI.a Lymphadenopathy (intrathoracic)

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.d Acute eosinophilic pneumonia (AEP)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.f Diffuse alveolar damage (DAD) imaging pattern

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.ab Chronic pneumonitis/ILD

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.ah Transient pulmonary opacities/infiltrates (see also under Iav)

XXV. Pulmonary function - Pulmonary physiology - PFTs

XXV.i A restrictive lung function defect

XXVIII. Large airway involvement

XXVIII.o A ‘tracheobronchitis’ clinical pattern

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXX. Imaging features

XXX.u Imaging: Reverse ventilation-perfusion mismatch

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.u Pulmonary vasculitis or capillaritis

XII. Pericardial involvement

XII.c Hemopericardium - Bloody pericardial effusion

XII. Pericardial involvement

XII.e Constrictive pericarditis - Pericardial thickening

XIV. Pleural involvement

XIV.e Hemothorax - Serosanguineous pleural effusion

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.a Hemomediastinum - Mediastinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.b Pulmonary hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXXII. Esophageal pathology

XXXII.a Esophageal hematoma (may cause chest pain and/or tracheal compression)