The Drug-Induced Respiratory Disease Website

I - Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.m

Sudden cardiac death

1

Evidence level

low

V - Myocarditis

V.a

Myocarditis (can be fulminate/fulminant)

1

Evidence level

low

VII - Cardiotoxicity

VII.a

‘Cardiotoxicity’

1

Evidence level

low

XIV - Pleural involvement

XIV.a

Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

1

Evidence level

low

XV - Chest pain

XV.e

Pleuritis (can cause chest pain)

1

Evidence level

low

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a

Pneumonitis (ILD)

1

Evidence level

low

XXIV.b

Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1

Evidence level

low

XXXVI - Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b

Lupus - Lupus syndrome

1

Evidence level

low

XXXVI.f

Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

1

Evidence level

low

XXXVI.ac

Antisynthetase antibodies (ASA) - ASA syndrome

1

Evidence level

low