The Drug-Induced Respiratory Disease Website

II - Myocardial dysfunction - Heart failure

II.a

Left ventricular dysfunction/failure

1

Evidence level

low

VI - Cardiomyopathy

VI.a

Cardiomyopathy (acute, subacute, chronic)

1

Evidence level

low

VI.c

Takotsubo (stress) cardiomyopathy

1

Evidence level

low

VII - Cardiotoxicity

VII.a

‘Cardiotoxicity’

2

Evidence level

possible

XI - Pulmonary vasculopathies

XI.a

Pulmonary arterial hypertension

1

Evidence level

low

XIII - Thrombosis - Embolism

XIII.a

Pulmonary embolism - Venous thrombosis/thrombo-embolism

2

Evidence level

possible

XIII.o

Systemic arterial thrombosis

1

Evidence level

low

XIV - Pleural involvement

XIV.k

Esophageal pleural fistula

1

Evidence level

low

XVI - Hemorrhage - Bleeding - Hematoma(s)

XVI.e

Alveolar hemorrhage (AH), diffuse AH (DAH)

1

Evidence level

low

XVI.i

Hemoptysis

1

Evidence level

low

XVI.j

Major/massive hemoptysis

1

Evidence level

low

XVI.o

Epistaxis

1

Evidence level

low

XVIII - Aortic involvement

XVIII.d

Aortitis

1

Evidence level

low

XX - Vasculitis

XX.d

Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive

1

Evidence level

low

XXII - Acute respiratory/cardiorespiratory failure

XXII.b

Acute lung injury - ARDS

1

Evidence level

low

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a

Pneumonitis (ILD)

1

Evidence level

low

XXIX - Small airway involvement

XXIX.a

Bronchospasm - Wheezing - Asthma

1

Evidence level

low

XXXVI - Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f

Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

1

Evidence level

low