Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

Statins

(A.k.a. HMG-CoA reductase inhibitors). Convincing cases reports of ILD contrast with the lack of epidemiological evidence (PMID 17223772, 23299962). Cerivastatin was recalled/discontinued worldwide in 2001, due to an excess rate of rhabdomyolysis, a complication common to statins and other lipid-lowering agents

XIV - Pleural involvement

XIV.a

Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV.o

Pleuroparenchymal fibroelastosis (PPFE)

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a

Pneumonitis (ILD)
XXIV.b

Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV.e

Relapsing or migrating pneumonitis/pneumonia (see also Id)
XXIV.h

Pulmonary fibrosis (may improve but partly following drug discontinuation)
XXIV.j

Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV.l

Acute fibrinous organizing pneumonia (AFOP)
XXIV.ai

The association of ILD and myositis

XXVIII - Large airway involvement

XXVIII.a

Angioedema (may cause UAO, asphyxia and death)

XXX - Imaging features

XXX.r

Imaging: Waxing and waning nodules