Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

Tocilizumab

For those ILD cases exposed to methotrexate concomitantly, drug causality assessment can be difficult. A meta-analysis in 2018 'did not reveal an increase in the risk of non-infectious respiratory AEs in adult patients with RA who were treated with tocilizumab compared with other DMARDs' (PMID 30183597)

XII - Pericardial involvement

XII.b

Pericardial effusion (w/wo tamponade)

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a

Pneumonitis (ILD)
XXIV.i

Progression, acceleration or exacerbation of preexisting ILD/fibrosis
XXIV.j

Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXVIII - Large airway involvement

XXVIII.d

Vocal cord dysfunction, adduction, closure

XXXIV - Infections

XXXIV.f

Opportunistic pulmonary/systemic infections

XXXVI - Autoimmune syndromes - Systemic reactions or conditions

XXXVI.c

Sarcoid-like granulomatosis (endo-/extrathoracic)