The Drug-Induced Respiratory Disease Website

Proton beam therapy

Esophageal pleural fistula

Pulmonary fibrosis (may improve but partly following drug discontinuation)

Focal/localized area of pneumonitis/fibrosis

Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

No activity has been recorded yet.