The Drug-Induced Respiratory Disease Website
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.k Pulmonary infiltrates
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.w Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
XXII. Acute respiratory/cardiorespiratory failure
XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXXV. Disordered breathing during sleep
XXXV.a Disordered breathing during sleep - Sleep apnea
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.g Generalized myopathy/muscle weakness
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
XX. Vasculitis
XX.d Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XIV. Pleural involvement
XIV.k Esophageal pleural fistula
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.t Focal/localized area of pneumonitis/fibrosis
XXXII. Esophageal pathology
XXXII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX. Small airway involvement
XXIX.i Exacerbation or deterioration of preexisting COPD
XXXIV. Infections
XXXIV.b Respiratory tract infection incl. pneumonia
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVIII. Miscellaneous - Varia
XXXVIII.k Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.ag Chemical (toxic) pneumonitis
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX. Small airway involvement
XXIX.k Cough, acute (can be violent and/or explosive)