The Drug-Induced Respiratory Disease Website

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.g Generalized myopathy/muscle weakness

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

X. Pulmonary edema

X.k Transfusion-related acute lung injury (TRALI) (May cause ARDS)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.e Bradycardia

IV. Heart block (bundle branch-, AV-block)

IV.a Heart block (bundle branch- or AV-)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

XIII. Thrombosis - Embolism

XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.k Multiple organ dysfunction/failure (MODS/MOF)

XII. Pericardial involvement

XII.c Hemopericardium - Bloody pericardial effusion

XII. Pericardial involvement

XII.e Constrictive pericarditis - Pericardial thickening

XIV. Pleural involvement

XIV.e Hemothorax - Serosanguineous pleural effusion

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XX. Vasculitis

XX.d Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive

XXVIII. Large airway involvement

XXVIII.i Tongue involvement (edema, glossitis, hematoma)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.ai The association of ILD and myositis

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.i Serositis - Polyserositis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXXIX. Rechallenge

XXXIX.e Rechallenge may not lead to relapse of the AE/ILD

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome