The Drug-Induced Respiratory Disease Website

Worsening of preexisting PHTn

Evidence not confirmed by all studies

Sadoughi A, Roberts KE, Preston IR, Lai GP, McCollister DH, Farber HW, Hill NS

Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension.

Chest 2013 Aug;144;531-541 — 2013 Aug — 531-541

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.