The Drug-Induced Respiratory Disease Website

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

II. Myocardial dysfunction - Heart failure

II.d Cardiovascular collapse - Cardiogenic shock - Hypotension

III. Myocardial ischemia - Coronary artery disease

III.c Coronary vasospasm - Vasospastic angina

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XI. Pulmonary vasculopathies

XI.f Worsening of preexisting PHTn

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.h Pleural thickening - Fibrothorax

XXII. Acute respiratory/cardiorespiratory failure

XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.e Relapsing or migrating pneumonitis/pneumonia (see also Id)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XXIX. Small airway involvement

XXIX.h Exacerbation or deterioration of preexisting asthma

XXIX. Small airway involvement

XXIX.i Exacerbation or deterioration of preexisting COPD

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.d Subclinical ANA positivity

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.l Refractoriness to epineprine in case of anaphylaxis

XXXVIII. Miscellaneous - Varia

XXXVIII.d Death following exposure or poisoning

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

XI. Pulmonary vasculopathies

XI.a Pulmonary arterial hypertension

XI. Pulmonary vasculopathies

XI.d Pulmonary hypertension of the newborn (Persistent PHT)

XI. Pulmonary vasculopathies

XI.f Worsening of preexisting PHTn

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.d Acute eosinophilic pneumonia (AEP)